Vitamin D And Male Reproduction

Document Type : Original Article

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Abstract

To study the relationship between vitamin D and male reproduction, fifty weanlings (21 days-old) male albino rats were obtained and divided into 2 groups, vitamin D-deficient group fed vitamin D-deficient diet and vitamin D-replete group fed the same diet but received a single intraperitoneal injection of 2 µg cholecalciferol per week (0.1 ml propylene glycol). The animals in both groups were maintained till became adult. The results revealed detection and expression of vitamin D receptor (VDR) gene in the testis of young rats at 2 months of age, a significant increase in acrosome reaction percentage, sperm motility and sperm count in the vitamin D-replete group, while sperm abnormalities were significantly higher in the vitamin D-deficient group. The results of this study suggest an important physiological role played by vitamin D in male reproductive biology. 

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