Molecular Comparison Between FMDV Causing Recent Outbreaks In Egypt And The Used Vaccine Strains

Document Type : Original Article

Authors

1 Virology Department, Faculty of Veterinary Medicine, Zagazig University, Egypt

2 FMD Department, Veterinary Serum and Vaccine Research Institute, Abbassia, Cairo

Abstract

Foot and mouth disease virus (FMD) had taken an enzootic form in Egypt since 1950, since then continues outbreaks occurs, serotype A, O and SAT2 are the most common serotypes isolated in Egypt. In this study, The suspected isolates were diagnosed and typed using an RT - PCR test. The nucleotide sequences of the VP1-coding region was determined and phylogenetic analysis was performed. The results showed that FMDV serotype O were confirmed to be serotype O topotype ME-SA in all localities,while the isolated type A during 2009 was confirmed to be serotype A topotype Africa, while the isolated type A during 2010 and 2011 belong to the Asia topotype and FMDV serotype SAT was confirmed to be SAT2 topotype VII.
 

Main Subjects