The Possible Effect of Bentonite Clay Powder in the Diet for Reducing Pymetrozine -Induced Oxidative Stress, Hepatorenal Dysfunction, and Pathological Alteration in Nile Tilapia
This study was aimed to assessing the impact of adding bentonite (BN) clay to the diet as an adsorbent for pymetrozine (PY) in Nile tilapia. Fish were randomly divided into a six triplicate groups. The first group (G1) was exposed to PY at a dose of 0.028 g L-1 (1/10 of 96 h LC50) + basal diet (Bd). The second group (G2) was exposed to PY at a dose of 0.014 g L-1 (1/20 of 96 h LC50) + Bd, whereas the third group (G3) was exposed to PY at a dose of 0.028 g L-1 (1/10 of 96 h LC50) + BN (5 g kg-1 diet). The fourth group (G4) was exposed to PY at a dose of 0.014 g L-1 (1/20 of 96 h LC50) + BN (5 g kg-1 diet), while the fifth group (G5) fed on BN (5 g kg-1 diet). The sixth group (G6) acts as a control group and is fed on a basal diet. There was a 60-day experimental period. In order to compare the examination of several markers and histological alterations, there was a 15-day withdrawal period. The aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), urea, and creatinine, were found to be significantly elevated (p < 0.05) in fish exposed to PY. Serum levels of acetylcholinesterase (AchE), catalase (CAT), copper zinc superoxide dismutase (Cu Zn-SOD), and reduced glutathione (GSH) significantly declined (p < 0.05), whereas the oxidative stress marker malondialdehyde (MDA) significantly enhanced (p < 0.05). The PY-intoxicated fish exhibited the more severe clinical symptoms and postmortem abnormalities. In the BN-treated groups (G3 and G4), the indications' intensity decreased. Notably, adding BN to the food of PY-intoxicated fish can lessen the abnormalities in the majority of the tissue architecture, clinical symptoms, postmortem lesions, and serum biochemical parameters of Nile tilapia.
Albohi, Z., Khalil, A., El-Hady, M., & Alhady, F. (2025). The Possible Effect of Bentonite Clay Powder in the Diet for Reducing Pymetrozine -Induced Oxidative Stress, Hepatorenal Dysfunction, and Pathological Alteration in Nile Tilapia. Zagazig Veterinary Journal, 53(1), 23-40. doi: 10.21608/zvjz.2024.328239.1264
MLA
Zainab Albohi; Alshymaa Khalil; Mohamed El-Hady; Fatma Alhady. "The Possible Effect of Bentonite Clay Powder in the Diet for Reducing Pymetrozine -Induced Oxidative Stress, Hepatorenal Dysfunction, and Pathological Alteration in Nile Tilapia", Zagazig Veterinary Journal, 53, 1, 2025, 23-40. doi: 10.21608/zvjz.2024.328239.1264
HARVARD
Albohi, Z., Khalil, A., El-Hady, M., Alhady, F. (2025). 'The Possible Effect of Bentonite Clay Powder in the Diet for Reducing Pymetrozine -Induced Oxidative Stress, Hepatorenal Dysfunction, and Pathological Alteration in Nile Tilapia', Zagazig Veterinary Journal, 53(1), pp. 23-40. doi: 10.21608/zvjz.2024.328239.1264
VANCOUVER
Albohi, Z., Khalil, A., El-Hady, M., Alhady, F. The Possible Effect of Bentonite Clay Powder in the Diet for Reducing Pymetrozine -Induced Oxidative Stress, Hepatorenal Dysfunction, and Pathological Alteration in Nile Tilapia. Zagazig Veterinary Journal, 2025; 53(1): 23-40. doi: 10.21608/zvjz.2024.328239.1264
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