• Home
  • Browse
    • Current Issue
    • By Issue
    • By Author
    • By Subject
    • Author Index
    • Keyword Index
  • Journal Info
    • About Journal
    • Aims and Scope
    • Editorial Board
    • Publication Ethics
    • Peer Review Process
  • Guide for Authors
  • Submit Manuscript
  • Reviewers
  • Contact Us
 
  • Login
  • Register
Home Articles List Article Information
  • Save Records
  • |
  • Printable Version
  • |
  • Recommend
  • |
  • How to cite Export to
    RIS EndNote BibTeX APA MLA Harvard Vancouver
  • |
  • Share Share
    CiteULike Mendeley Facebook Google LinkedIn Twitter
Zagazig Veterinary Journal
arrow Articles in Press
arrow Current Issue
Journal Archive
Volume Volume 48 (2020)
Issue Issue 4
Issue Issue 3
Issue Issue 2
Issue Issue 1
Volume Volume 47 (2019)
Volume Volume 46 (2018)
Volume Volume 45 (2017)
Volume Volume 44 (2016)
Volume Volume 43 (2015)
Volume Volume 42 (2014)
Volume Volume 41 (2013)
Hashem, M., Hashish, E., Atteya, M. (2020). Alternative Approaches to Ameliorate Nonalcoholic Fatty Liver Disease: Phyllanthus niruri Clinicopathological Significance; A review. Zagazig Veterinary Journal, 48(4), 399-413. doi: 10.21608/zvjz.2020.34050.1111
Mohamed Hashem; Emad Hashish; Marwa Atteya. "Alternative Approaches to Ameliorate Nonalcoholic Fatty Liver Disease: Phyllanthus niruri Clinicopathological Significance; A review". Zagazig Veterinary Journal, 48, 4, 2020, 399-413. doi: 10.21608/zvjz.2020.34050.1111
Hashem, M., Hashish, E., Atteya, M. (2020). 'Alternative Approaches to Ameliorate Nonalcoholic Fatty Liver Disease: Phyllanthus niruri Clinicopathological Significance; A review', Zagazig Veterinary Journal, 48(4), pp. 399-413. doi: 10.21608/zvjz.2020.34050.1111
Hashem, M., Hashish, E., Atteya, M. Alternative Approaches to Ameliorate Nonalcoholic Fatty Liver Disease: Phyllanthus niruri Clinicopathological Significance; A review. Zagazig Veterinary Journal, 2020; 48(4): 399-413. doi: 10.21608/zvjz.2020.34050.1111

Alternative Approaches to Ameliorate Nonalcoholic Fatty Liver Disease: Phyllanthus niruri Clinicopathological Significance; A review

Article 6, Volume 48, Issue 4, Autumn 2020, Page 399-413  XML PDF (616.2 K)
Document Type: Review Article
DOI: 10.21608/zvjz.2020.34050.1111
Authors
Mohamed Hashem; Emad Hashishorcid ; Marwa Atteya email
Clinical Pathology Department, Faculty of Veterinary Medicine, Zagazig University, 44511, Egypt
Abstract
Nonalcoholic fatty liver disease (NAFLD) is one of the major global health issues, strongly correlated with metabolic disorder, insulin resistance, obesity and oxidative stress.  It is characterized by an excessive accumulation of liver fat, inflammation and dysfunction of the hepatocytes. NAFLD predisposes to cirrhosis, cardiovascular disease, and hepatocellular carcinoma in susceptible individuals. Although the specific signals remain poorly understood, NAFLD pathogenesis can involve the behavior of different types of hepatic cells and several extra-hepatic signals. The difficulty of NAFLD has been a big impediment to advancement and effective therapies with appropriate indicators. NAFLD's alternative medicines with medicinal herbs become the most useful solution today because of their minimum side effects. Phyllanthus niruri (P. niruri) is an herbal medicine that contains various bioactive phytochemicals with hypolipidemic, antioxidant, detoxifying, antimutagenic, anti-inflammatory and antiviral activities. The reduction of fatty acids and decreased insulin resistance (IR) is expected after P. niruri administration, which helps in the prevention of NAFLD. In this review, we describe recent clinical and diagnostic methods examining the diagnosis, development, and effects of NAFLD; comparing the attributes of the genetic and dietary animal models of NAFLD; and highlighting the potential hepatoprotective function of P. niruri, plus its therapeutic role in the prevention of NAFLD.
Keywords
NAFLD; Phyllanthus niruri; Clinicopathological assays
Main Subjects
Clinical Science, Surgery and Veterinary Diseases (Pathology, Clinical Pathology, Internal Medicine, Infectious Diseases, Poultry Diseases, Fish Diseases and Management, Surgery, Theriogenology)
Statistics
Article View: 26
PDF Download: 34
Home | Glossary | News | Aims and Scope | Sitemap
Top Top

Journal Management System. Designed by NotionWave.